(2005) Journal of Investigative Dermatology 125, 805-17 “Altered Melanocyte Differentiation and RPE Transdifferentiation Induced by Mash1 Expression in Pigment Cell Precursors”. Lanning, J.L., Wallace, J.S., Zhang, D., Diwakar, G., Jiao, Z., & Hornyak, T.J. “Direct Interaction of Sox10 with the Promoter of Murine Dopachrome tautomerase (Dct) and Synergistic Activation of Dct Expression with Mitf”. Jiao, Z., Mollaaghababa, R., Pavan, W.J., Antonellis, A., Green, E.D., & Hornyak, T.J. “Diagnostic Value of HMB-45 and Anti-Melan A Staining of Sentinel Lymph Nodes with Isolated Positive Cells”. Mahmood, M.N., Lee, M.W., Linden, M.D., Nathanson, S.D., Hornyak, T.J., & Zarbo, R.J. “Analysis of SOX10 function in neural crest-derived melanocyte development: SOX10-dependent transcriptional control of dopachrome tautomerase”. Potterf, S.B., Mollaaghababa, R., Hou, L., Southard-Smith, E.M., Hornyak, T.J., Arnheiter, H., Pavan, W.J. At the National Cancer Institute, he developed a clinical protocol utilizing digital dermatoscopy to image selected melanocytic nevi on melanoma-prone patients in a serial manner, using clinical samples of nevi and melanoma to define the role of the Polycomb protein and histone methyltransferase EZH2 in suppressing senescence in melanoma cells. Hornyak extended his work in developmental pigment cell biology to melanocyte stem cells and melanoma epigenetics in the Dermatology Branch of the National Cancer Institute, where he developed a transgenic mouse system to isolate and characterize melanocyte stem cells. He completed this work as an independent investigator at the Henry Ford Health System in Detroit.ĭr. Hornyak described both the transcriptional biochemistry and the developmental determinants of early melanocyte development in the embryo. Hornyak completed a residency in clinical dermatology and began research on melanocytes as a post-doctoral fellow at New York University. in Biological Chemistry emphasizing enzymology and medical training, Dr. His current position titles are Chair, Department of Dermatology, VA Maryland Health Care System Associate Professor of Dermatology and Biochemistry and Molecular Biology, University of Maryland School of Medicine and Associate Chief of Staff for Research & Development, VA Maryland Health Care System.įolIowing completion of a Ph.D. Thomas Hornyak is an internationally recognized physician scientist in pigment cell biology, melanoma and skin cancer. Institute for Neuroscience Discovery (UM-MIND)ĭr.Center for Vascular & Inflammatory Diseases.Center for Vaccine Development and Global Health (CVD).Center for Stem Cell Biology & Regenerative Medicine.Center for Shock, Trauma and Anesthesiology Research.Maryland Psychiatric Research Center (MPRC).Center for Epigenetic Research in Child Health & Brain Development.Center for Biomolecular Therapeutics (CBT).Center for Biomedical Engineering and Technology. Center for Advanced Research Training & Innovation (CARTI).Aging, Trauma, and Emergency Care (PATEC).Physical Therapy and Rehabilitation Science.Otorhinolaryngology - Head and Neck Surgery.Obstetrics, Gynecology and Reproductive Sciences.Diagnostic Radiology and Nuclear Medicine.
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